Muscle Shoals is a medium-sized city located in the state of Alabama. With a population of 17,210 people and five associated neighborhoods, Muscle Shoals is the 41st largest community in Alabama.

Telecommuters are a relatively large percentage of the workforce: 9.42% of people work from home. While this number may seem small overall, as a fraction of the total workforce it is high relative to the nation. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

Being a small city, Muscle Shoals does not have a public transit system used by locals to get to and from work.

The population of Muscle Shoals overall has a level of education that is slightly above the US average for all US cities and towns of 21.84%. Of adults 25 and older in Muscle Shoals, 21.19% have at least a bachelor's degree.

The per capita income in Muscle Shoals in 2022 was $35,791, which is wealthy relative to Alabama, and upper middle income relative to the rest of the US. This equates to an annual income of $143,164 for a family of four. However, Muscle Shoals contains both very wealthy and poor people as well.

Muscle Shoals is a very ethnically-diverse city. The people who call Muscle Shoals home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Muscle Shoals residents report their race to be White, followed by Black or African-American. Important ancestries of people in Muscle Shoals include English, Irish, German, Italian, and European.

The most common language spoken in Muscle Shoals is English. Other important languages spoken here include Spanish and Langs. of India.