De Soto is a somewhat small city located in the state of Missouri. With a population of 6,493 people and four associated neighborhoods, De Soto is the 112th largest community in Missouri.

One interesting thing about the economy is that relatively large numbers of people worked from their home: 15.11% of the workforce. While this number may seem small overall, as a fraction of the total workforce this is high compared to the rest of the county. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

One downside of living in De Soto, however, is that residents on average have to contend with a long commute, spending on average 33.26 minutes every day commuting to work.

The percentage of people in De Soto with college degrees is quite a bit lower than the national average for cities and towns of 21.84%: just 11.32% of people over 25 have a bachelor's degree or advanced degree.

The per capita income in De Soto in 2022 was $24,680, which is lower middle income relative to Missouri, and low income relative to the rest of the US. This equates to an annual income of $98,720 for a family of four. However, De Soto contains both very wealthy and poor people as well.

De Soto is a somewhat ethnically-diverse city. The people who call De Soto home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of De Soto residents report their race to be White, followed by Native American. Important ancestries of people in De Soto include German, English, Irish, Italian, and Dutch.

The most common language spoken in De Soto is English. Other important languages spoken here include Italian and Spanish.